HitPredict

Interactor 1: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Interactor 2: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 23602568
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0051301 - cell division
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 410
Hs

1 305
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024