HitPredict

Interactor 1: AT2B1 (P20020)
Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)
Gene: ATP2B1

Interactor 2: AT2B1 (P20020)
Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)
Gene: ATP2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase~E1-E2_ATPase, Cation_ATPase~Hydrolase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase, Hydrolase~Hydrolase
Common GO terms GO:0001772 - immunological synapse
GO:0001818 - negative regulation of cytokine production
GO:0003056 - regulation of vascular associated smooth muscle contraction
GO:0005388 - P-type calcium transporter activity
GO:0005516 - calmodulin binding
and 25 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1220
Hs

1 1220
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Last updated: 11Aug2025