Interactor 1: NOT1 (P25655)
General negative regulator of transcription subunit 1 (Cell division cycle protein 39)
Gene: CDC39

Interactor 2: POP2 (P39008)
Poly(A) ribonuclease POP2 (EC 3.1.13.4) (CCR4-associated factor 1)
Gene: POP2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 9463387, 10490603, 24121231, 11805826, 11733989, 16429126, 16263706, 30948432, 18467557, 37968396, 20386698, 22959269, 21669201, 14734555, 12215412, 19107399
Identification Methods coimmunoprecipitation, two hybrid, tandem affinity purification, affinity chromatography technology, biochemical, protein complementation assay, x-ray crystallography, pull down, anti bait coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1~CNOT1_CAF1_bind
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006368 - transcription elongation by RNA polymerase II
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 2108
Sc

1 433
+ Hs
+ Mm
+ Hs
+ Sp
+ Dm
+ Dm
+ Dm
+ Ce

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Last updated: 15 Jul 2024