Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: DOA10 (P40318)
ERAD-associated E3 ubiquitin-protein ligase DOA10 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase DOA10)
Gene: SSM4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 37968396, 16873066, 20579315, 16179953, 23665229, 16179952
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000837 - Doa10p ubiquitin ligase complex
GO:0005789 - endoplasmic reticulum membrane
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 835
Sc

1 1319
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024