HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain)
Gene: PSMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 263
+	Hs
		637529 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Hs
		689 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	Hs
		699 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	Hs
		688 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	Hs
		156342 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		656297 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	Hs
		893734 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	Hs
		638180 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	Dm
		522504 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA1_DROME (1-260): 4.06e-99: 292: 52.42
+	Dm
		1278636 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA5_DROME (1-237): 4.05e-92: 273: 28.86
+	Dm
		611652 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA71_DROME (4-233): 2.4e-38: 136: 33.48
+	Sc
		693310 RPN2_YEAST (2-914): 0: 919: 38.04		PSA6_YEAST (1-233): 3.26e-83: 250: 52.77
+	Hs
		637407 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA1_HUMAN (1-263): 3.26e-109: 317: 100.00
+	Hs
		156281 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA7_HUMAN (6-234): 9.99e-96: 282: 33.19
+	Hs
		656214 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA5_HUMAN (1-236): 5.66e-93: 275: 28.81
+	Hs
		893662 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA6_HUMAN (1-240): 1.64e-92: 274: 25.00
+	Hs
		638122 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA4_HUMAN (1-233): 4.82e-91: 271: 28.75
+	Dm
		522523 Q9VW54_DROME (12-712): 0: 614: 18.02		PSA1_DROME (1-260): 4.06e-99: 292: 52.42
+	Dm
		1278652 Q9VW54_DROME (12-712): 0: 614: 18.02		PSA5_DROME (1-237): 4.05e-92: 273: 28.86
+	Dm
		611672 Q9VW54_DROME (12-712): 0: 614: 18.02		PSA71_DROME (4-233): 2.4e-38: 136: 33.48