HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: OTUD1 (Q5VV17)
OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)
Gene: OTUD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	36579465, 36929488, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 481
+	Hs
		278102 FLNB_HUMAN (28-2647): 0: 2710: 69.63		OTUD1_HUMAN (1-481): 7.82e-100: 310: 100.00
+	Hs
		637682 FLNA_HUMAN (1-2647): 0: 2776: 100.00		OTUD5_HUMAN (135-439): 4.46e-48: 176: 20.00
+	Hs
		637660 FLNA_HUMAN (1-2647): 0: 2776: 100.00		TITIN_HUMAN (14-299): 2.84e-12: 71.6: 13.40
+	Hs
		1125347 FLNC_HUMAN (32-2647): 0: 1436: 35.86		OTUD1_HUMAN (1-481): 7.82e-100: 310: 100.00
+	Hs
		1032307 FLNC_HUMAN (32-2647): 0: 1436: 35.86		OTUD4_HUMAN (293-442): 3.1e-31: 129: 26.00
+	Hs
		224725 ACTN4_HUMAN (23-459): 3.26e-115: 392: 24.06		OTUD3_HUMAN (246-478): 9.67e-63: 211: 19.83
+	Hs
		773767 ACTN2_HUMAN (6-459): 1.09e-120: 408: 23.62		TITIN_HUMAN (14-299): 2.84e-12: 71.6: 13.40
+	Hs
		1061541 ACTN3_HUMAN (30-460): 1.52e-117: 398: 25.28		TITIN_HUMAN (14-299): 2.84e-12: 71.6: 13.40
+	Hs
		555729 ACTN1_HUMAN (21-459): 1.48e-117: 398: 24.18		TITIN_HUMAN (14-299): 2.84e-12: 71.6: 13.40
+	Hs
		224763 ACTN4_HUMAN (23-459): 3.26e-115: 392: 24.06		TITIN_HUMAN (14-299): 2.84e-12: 71.6: 13.40
+	Hs
		62028 A4D1J9_HUMAN (1378-1539): 5.24e-15: 80.5: 33.50		OTUD1_HUMAN (1-481): 7.82e-100: 310: 100.00