HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: FLIP1 (Q7Z7B0)
Filamin-A-interacting protein 1 (FILIP)
Gene: FILIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	12055638
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0021987 - cerebral cortex development and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2647 Hs			1 1213
+	Hs
		637375 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYH11_HUMAN (35-1081): 2.03e-45: 181: 10.29
+	Hs
		637373 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYH9_HUMAN (87-1124): 1.29e-43: 176: 10.85
+	Hs
		156952 FLNA_HUMAN (1-2647): 0: 2776: 100.00		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		278027 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MYH9_HUMAN (87-1124): 1.29e-43: 176: 10.85
+	Hs
		637751 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MYO5C_HUMAN (154-658): 8.91e-12: 72: 22.12
+	Hs
		637609 FLNA_HUMAN (1-2647): 0: 2776: 100.00		LUZP1_HUMAN (146-546): 5.63e-11: 69.3: 19.20
+	Hs
		156763 FLNB_HUMAN (28-2647): 0: 2710: 69.63		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		637663 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Hs
		278132 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38
+	Hs
		157367 FLNC_HUMAN (32-2647): 0: 1436: 35.86		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		772748 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		MYH9_HUMAN (87-1124): 1.29e-43: 176: 10.85
+	Hs
		555621 ACTN1_HUMAN (21-459): 1.48e-117: 398: 24.18		MYH9_HUMAN (87-1124): 1.29e-43: 176: 10.85
+	Hs
		157250 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		157023 ACTN2_HUMAN (6-459): 1.09e-120: 408: 23.62		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		156898 ACTN1_HUMAN (21-459): 1.48e-117: 398: 24.18		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		157282 ACTN3_HUMAN (30-460): 1.52e-117: 398: 25.28		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		156889 SPTB1_HUMAN (12-345): 2.21e-110: 396: 29.11		CTRO_HUMAN (20-666): 2.38e-30: 133: 11.57
+	Hs
		1028778 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		ITSN1_HUMAN (38-382): 2.01e-15: 84.1: 9.86
+	Hs
		1028889 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		MYO5C_HUMAN (154-658): 8.91e-12: 72: 22.12
+	Hs
		1028834 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		MY18A_HUMAN (181-697): 1.39e-09: 65.1: 18.38