HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9250404
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 840
+	Hs
		714162 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		714414 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320835 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		320911 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		503471 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		639682 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Mm
		926175 IKBA_MOUSE (1-317): 2.2e-78: 243: 91.17		HSP7C_MOUSE (564-692): 1.76e-19: 95.5: 16.15
+	Hs
		121564 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		121572 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		503906 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Mm
		638457 NFKB1_MOUSE (70-302): 5.46e-66: 224: 38.98		HS71A_MOUSE (571-686): 1e-17: 89.7: 23.08
+	Hs
		713945 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		564057 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		503916 ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		483759 ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50		HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		503777 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504758 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		714021 ANKK1_HUMAN (152-310): 1.44e-32: 129: 21.38		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		564048 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564185 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86