HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: SUMO4 (Q6EEV6)
Small ubiquitin-related modifier 4 (SUMO-4) (Small ubiquitin-like protein 4)
Gene: SUMO4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	15247916, 19222990
Identification Methods	two hybrid, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 95
+	Hs
		639715 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		SUMO2_HUMAN (1-95): 4.5e-41: 132: 85.26
+	Rn
		94035 IKBA_RAT (1-317): 2.79e-78: 242: 90.85		F1LN30_RAT (1-95): 1.5e-39: 128: 81.05
+	Hs
		928063 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		SUMO1_HUMAN (1-93): 4.7e-35: 116: 38.14
+	Hs
		928130 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		SUMO1_HUMAN (1-93): 4.7e-35: 116: 38.14