Protein: ATAD2
ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA)

Gene: ATAD2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q6PL18

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006334 - nucleosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396352

ESR1
Estrogen receptor

4

20

Small-scale

0.701

High

372347

MYC
Myc proto-oncogene protein

3

6

Small-scale

0.664

High

998457

H31
Histone H3.1

3

16

High-throughput

0.640

High

1141184

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.618

High

1245819

UBQL2
Ubiquilin-2

1

20

High-throughput

0.618

High

487447

PARP1
Poly [ADP-ribose] polymerase 1

2

6

High-throughput

0.584

High

980860

H2B1C
Histone H2B type 1-C/E/F/G/I

2

10

High-throughput

0.584

High

995092

CSK2B
Casein kinase II subunit beta

2

4

High-throughput

0.571

High

143450

E2F3
Transcription factor E2F3

1

3

Small-scale

0.561

High

1029105

E2F1
Transcription factor E2F1

1

3

Small-scale

0.561

High

1156748

E2F4
Transcription factor E2F4

1

3

Small-scale

0.561

High

1245817

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.546

High

336697

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.541

High

1132379

CASP8
Caspase-8

1

5

High-throughput

0.541

High

74523

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.536

High

997800

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.536

High

1013074

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

3

High-throughput

0.536

High

1134618

NUMA1
Nuclear mitotic apparatus protein 1

1

8

High-throughput

0.536

High

1162999

H2B2E
Histone H2B type 2-E

1

10

High-throughput

0.536

High

1245810

HDA11
Histone deacetylase 11

1

8

High-throughput

0.536

High

1245820

NCOA3
Nuclear receptor coactivator 3

1

4

Small-scale

0.534

High

979855

H4
Histone H4

1

6

Small-scale

0.501

High

1124148

E2F2
Transcription factor E2F2

1

3

Small-scale

0.501

High

1161909

H31T
Histone H3.1t

1

16

Small-scale

0.501

High

294870

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

5

High-throughput

0.494

High

129196

MEN1
Menin

1

3

High-throughput

0.479

High

345964

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

374694

RASH
GTPase HRas

1

8

High-throughput

0.479

High

613083

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

883585

CENPA
Histone H3-like centromeric protein A

1

16

High-throughput

0.479

High

962178

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

975760

RL7A
Large ribosomal subunit protein eL8

1

5

High-throughput

0.479

High

1016961

H33
Histone H3.3

1

16

High-throughput

0.479

High

1097365

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

1100843

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.479

High

1106966

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1125134

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

9

Small-scale

0.479

High

1150868

CIP4
Cdc42-interacting protein 4

1

3

High-throughput

0.479

High

1161500

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1198180

PDCD4
Programmed cell death protein 4

1

4

High-throughput

0.479

High

1245800

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

1245802

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1245805

NUP43
Nucleoporin Nup43

1

13

High-throughput

0.479

High

1245807

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1245808

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

1245811

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

13

High-throughput

0.479

High

1245812

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.479

High

1245813

WDR76
WD repeat-containing protein 76

1

13

High-throughput

0.479

High

1245814

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

1245815

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

174770

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

8

High-throughput

0.470

High

1245806

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

191886

MAGB3
Melanoma-associated antigen B3

1

7

High-throughput

0.445

High

649341

H1T
Histone H1t

1

2

High-throughput

0.445

High

1023560

CYC
Cytochrome c

1

2

High-throughput

0.445

High

1245803

HDGR2
Hepatoma-derived growth factor-related protein 2

1

3

High-throughput

0.445

High

1245804

RNF10
E3 ubiquitin-protein ligase RNF10

1

7

High-throughput

0.445

High

1245801

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

1245809

VP33A
Vacuolar protein sorting-associated protein 33A

1

3

High-throughput

0.437

High

50908

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.426

High

634851

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.426

High

1232365

SFRP4
Secreted frizzled-related protein 4

1

0

High-throughput

0.426

High

1245818

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.426

High

635890

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

1

High-throughput

0.407

High

1226902

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.407

High

1245816

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.249

Low

1244150

TT23L
Tetratricopeptide repeat protein 23-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025