HitPredict

Interactor 1: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	27880917, 27432908, 28330616, 28675297, 9341175, 33961781, 36931259, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 246
+	Hs
		640229 PTN3_HUMAN (1-913): 0: 856: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		640230 PTN3_HUMAN (1-913): 0: 856: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		640212 PTN3_HUMAN (1-913): 0: 856: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		663970 PTN4_HUMAN (1-913): 0: 804: 50.11		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		663962 PTN4_HUMAN (1-913): 0: 804: 50.11		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		663973 PTN4_HUMAN (1-913): 0: 804: 50.11		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		640228 PTN3_HUMAN (1-913): 0: 856: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		640237 PTN3_HUMAN (1-913): 0: 856: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		646653 PTN4_HUMAN (1-913): 0: 804: 50.11		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		640217 PTN3_HUMAN (1-913): 0: 856: 100.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		663969 PTN4_HUMAN (1-913): 0: 804: 50.11		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		663976 PTN4_HUMAN (1-913): 0: 804: 50.11		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		683499 FRMD5_HUMAN (18-476): 6.87e-131: 406: 27.02		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		683710 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647056 FRMD5_HUMAN (18-476): 6.87e-131: 406: 27.02		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		647274 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904784 FRMD5_HUMAN (18-476): 6.87e-131: 406: 27.02		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		905110 E41L1_HUMAN (8-659): 9.72e-126: 403: 23.67		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Mm
		935597 FARP2_MOUSE (18-474): 7.18e-125: 405: 26.76		1433F_MOUSE (4-244): 8.67e-108: 312: 75.51
+	Hs
		982212 FRMD5_HUMAN (18-476): 6.87e-131: 406: 27.02		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51