HitPredict

Interactor 1: CLH (P22137)
Clathrin heavy chain
Gene: CHC1

Interactor 2: AP18A (P38856)
Clathrin coat assembly protein AP180A
Gene: YAP1801

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	9531549, 39511183
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0048268 - clathrin coat assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1653 Sc			1 637
+	Hs
		1026016 CLH1_HUMAN (4-1648): 0: 2877: 49.76		PICAL_HUMAN (2-632): 1.8e-117: 366: 20.09
+	Hs
		271698 CLH1_HUMAN (4-1648): 0: 2877: 49.76		HIP1R_HUMAN (3-320): 2.46e-80: 276: 14.75
+	Hs
		130942 CLH1_HUMAN (4-1648): 0: 2877: 49.76		HIP1_HUMAN (3-307): 7.88e-77: 266: 14.15
+	Hs
		922428 CLH2_HUMAN (4-1635): 0: 2756: 48.90		PICAL_HUMAN (2-632): 1.8e-117: 366: 20.09
+	Hs
		252758 CLH1_HUMAN (4-1648): 0: 2877: 49.76		AP180_HUMAN (2-492): 3.46e-68: 241: 19.29
+	Hs
		130929 CLH2_HUMAN (4-1635): 0: 2756: 48.90		HIP1_HUMAN (3-307): 7.88e-77: 266: 14.15
+	Hs
		114515 CLH1_HUMAN (4-1648): 0: 2877: 49.76		H0YEF7_HUMAN (278-604): 2.84e-32: 128: 15.66
+	Hs
		252755 CLH2_HUMAN (4-1635): 0: 2756: 48.90		AP180_HUMAN (2-492): 3.46e-68: 241: 19.29
+	At
		1081958 CLAH1_ARATH (2-1642): 0: 2625: 43.39		AP180_ARATH (1-578): 7.63e-89: 291: 15.71
+	Sc
		644817 CLH_YEAST (1-1653): 0: 2505: 100.00		AP18B_YEAST (2-563): 3.43e-89: 289: 44.21
+	Sc
		644744 CLH_YEAST (1-1653): 0: 2505: 100.00		SLA2_YEAST (2-380): 7.1e-70: 246: 12.53