HitPredict

Interactor 1: SMCA1 (P28370)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: SMARCA1

Interactor 2: CECR2 (Q9BXF3)
Chromatin remodeling regulator CECR2 (Cat eye syndrome critical region protein 2)
Gene: CECR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	31753913, 35271311, 15640247
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0090537 - CERF complex GO:0140658 - ATP-dependent chromatin remodeler activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1054 Hs			1 1484
+	Hs
		229482 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		CECR2_HUMAN (1-1484): 0: 1860: 100.00
+	Hs
		658750 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		BAZ2B_HUMAN (379-539): 2.06e-41: 169: 27.33
+	Hs
		658751 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		BAZ1B_HUMAN (387-579): 6.22e-40: 164: 24.35
+	Hs
		658659 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		BPTF_HUMAN (436-536): 3.87e-36: 152: 40.59
+	Mm
		102332 SMCA1_MOUSE (1-1054): 0: 1138: 94.71		G3UWZ0_MOUSE (383-532): 4.23e-31: 135: 26.67
+	Hs
		658742 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		BAZ1A_HUMAN (386-532): 2.28e-31: 136: 27.89
+	Hs
		229448 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		PHIP_HUMAN (388-812): 6.07e-50: 197: 14.84
+	Hs
		631352 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		BRD2_HUMAN (403-542): 1.23e-24: 113: 29.58
+	Hs
		229518 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BAZ2B_HUMAN (379-539): 2.06e-41: 169: 27.33
+	Mm
		1265296 SMCA5_MOUSE (73-1051): 0: 1068: 84.88		BAZ1B_MOUSE (388-561): 8.45e-40: 164: 25.13
+	Hs
		229520 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BAZ1B_HUMAN (387-579): 6.22e-40: 164: 24.35
+	Hs
		229455 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		KAT2A_HUMAN (404-537): 3.04e-40: 163: 31.34
+	Hs
		229378 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BPTF_HUMAN (436-536): 3.87e-36: 152: 40.59
+	Hs
		229519 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BAZ2A_HUMAN (396-545): 7.43e-33: 141: 28.00
+	Mm
		101401 SMCA5_MOUSE (73-1051): 0: 1068: 84.88		F8VPM0_MOUSE (420-545): 9.28e-32: 137: 28.57
+	Mm
		1265217 SMCA5_MOUSE (73-1051): 0: 1068: 84.88		BAZ2A_MOUSE (420-545): 9.93e-32: 137: 28.57
+	Mm
		102334 SMCA5_MOUSE (73-1051): 0: 1068: 84.88		G3UWZ0_MOUSE (383-532): 4.23e-31: 135: 26.67
+	Mm
		291490 SMCA5_MOUSE (73-1051): 0: 1068: 84.88		BAZ1A_MOUSE (383-532): 4.2e-31: 135: 26.67
+	Hs
		229505 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BAZ1A_HUMAN (386-532): 2.28e-31: 136: 27.89
+	Hs
		229311 SMCA5_HUMAN (32-1051): 0: 1065: 81.86		BRD2_HUMAN (403-542): 1.23e-24: 113: 29.58