HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.50	0.506

Property	Details
Experiments	20591429
Identification Methods	pull down, molecular sieving, surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 491
+	Hs
		642935 S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		615210 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		962851 HORN_HUMAN (2-90): 2.84e-32: 119: 28.09		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		380767 S100B_HUMAN (4-92): 8.65e-33: 111: 44.94		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		416609 S10A6_HUMAN (2-93): 1.75e-30: 104: 46.74		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		169242 S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		169240 S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		169226 S100B_HUMAN (4-92): 8.65e-33: 111: 44.94		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		169246 S10A5_HUMAN (2-91): 7.41e-26: 93.4: 53.33		MDM4_HUMAN (4-489): 0: 531: 32.08