Interactor 1: RIR1 (P23921)
Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit)
Gene: RRM1
Interactor 2: RIR2B (Q7LG56)
Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2)
Gene: RRM2B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.923 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ATP-cone~Ribonuc_red_sm, Ribonuc_red_lgC~Ribonuc_red_sm |
| Common GO terms | GO:0000731 - DNA synthesis involved in DNA repair GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005971 - ribonucleoside-diphosphate reductase complex and 7 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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| + | Mm |   |
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| + | Dm | |
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| + | Sp | |
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| + | Sc | |
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| + | Vv | |
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| + | Sc | |
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| + | Ec | |
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| + | Hh | |
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| + | Ha | |
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| + | Hh | |
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| + | Hh | |
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| + | Mp | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
