HitPredict

Interactor 1: PAX3 (P24610)
Paired box protein Pax-3
Gene: PAX3

Interactor 2: LEF1 (P27782)
Lymphoid enhancer-binding factor 1 (LEF-1)
Gene: LEF1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.629

The method score is based on:

Property Details
Experiments 20006729, 15729346
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003682 - chromatin binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 479
Mm

1 397
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Xl

Service provided by Combinatics, Japan

Last updated: 11Aug2025