Interactor 1: MPIP3 (P30307)
M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)
Gene: CDC25C
Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23567337, 11202906, 19503101, 19597481, 17307877, 14532005, 12595692 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, x-ray crystallography, classical fluorescence spectroscopy, anti bait coimmunoprecipitation, isothermal titration calorimetry, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Rhodanese |
| Common GO terms | GO:0000086 - G2/M transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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| + | Hs |   |
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| + | Dm | |
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| + | Sc |  |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
