Interactor 1: CENPX (A8MT69)
Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog)
Gene: CENPX

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.90 0.875

The method score is based on:

Property Details
Experiments 20347428, 26625197, 24699063, 22510687, 20347429
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-X~FANCM-MHF_bd
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0000785 - chromatin
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031297 - replication fork processing
and 3 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024