HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB9A (P51151)
Ras-related protein Rab-9A
Gene: RAB9A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.952

Property	Details
Experiments	26496610, 7744738, 35271311, 28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0015031 - protein transport GO:0032482 - Rab protein signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 201
+	Hs
		678358 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		678331 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (2-201): 3.43e-79: 236: 32.68
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (2-201): 3.43e-79: 236: 32.68
+	Hs
		838645 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB35_HUMAN (1-201): 1.97e-87: 257: 36.72
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (2-201): 1.7e-77: 232: 32.02
+	Hs
		838606 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB7A_HUMAN (2-200): 5.12e-86: 254: 50.24
+	Hs
		678336 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB8A_HUMAN (1-199): 2.22e-76: 229: 35.12
+	Hs
		678381 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB8B_HUMAN (1-199): 2.86e-76: 229: 35.12
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (3-201): 6.93e-74: 223: 32.71
+	Hs
		838607 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB9A_HUMAN (1-201): 1.55e-82: 245: 100.00
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (2-201): 3.43e-79: 236: 32.68
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (2-201): 1.7e-77: 232: 32.02
+	Hs
		838616 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB8A_HUMAN (1-199): 2.22e-76: 229: 35.12
+	Hs
		838673 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB8B_HUMAN (1-199): 2.86e-76: 229: 35.12
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (3-201): 3.4e-75: 227: 35.38
+	Hs
		838647 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11B_HUMAN (3-201): 6.93e-74: 223: 32.71
+	Dm
		185501 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18332_DROME (2-201): 1.97e-76: 229: 32.84
+	Dm
		185708 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18335_DROME (7-172): 3.78e-39: 135: 40.72