Protein: RSC6
Chromatin structure-remodeling complex protein RSC6 (Remodel the structure of chromatin complex subunit 6)

Gene: RSC6
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P25632

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005198 - structural molecule activity
GO:0005634 - nucleus
GO:0006337 - nucleosome disassembly
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678348

RSC2
Chromatin structure-remodeling complex subunit RSC2

13

20

Small-scale

0.758

High

678329

RSC8
Chromatin structure-remodeling complex protein RSC8

10

18

Small-scale

0.758

High

678306

STH1
Nuclear protein STH1/NPS1

11

20

Small-scale

0.756

High

678346

SFH1
Chromatin structure-remodeling complex subunit SFH1

6

6

Small-scale

0.732

High

678335

RSC4
Chromatin structure-remodeling complex subunit RSC4

6

20

High-throughput

0.732

High

678309

RSC7
Chromatin structure-remodeling complex subunit RSC7

5

1

High-throughput

0.718

High

678349

RSC3
Chromatin structure-remodeling complex protein RSC3

5

1

High-throughput

0.718

High

678333

RT102
Regulator of Ty1 transposition protein 102

5

1

High-throughput

0.716

High

678344

ARP9
Actin-like protein ARP9

5

18

High-throughput

0.716

High

678350

RSC58
Chromatin structure-remodeling complex protein RSC58

7

0

Small-scale

0.713

High

678332

RSC1
Chromatin structure-remodeling complex subunit RSC1

5

20

Small-scale

0.709

High

678338

RSC9
Chromatin structure-remodeling complex subunit RSC9

6

0

Small-scale

0.697

High

678355

ARP7
Actin-related protein 7

4

15

High-throughput

0.697

High

381903

H4
Histone H4

4

2

Small-scale

0.676

High

678318

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

18

High-throughput

0.662

High

678324

ATAD2
ATPase histone chaperone YTA7

4

0

Small-scale

0.643

High

678334

H3
Histone H3

3

4

Small-scale

0.641

High

419621

H2A2
Histone H2A.2

3

3

High-throughput

0.633

High

678360

HTL1
High temperature lethal protein 1

3

0

High-throughput

0.616

High

543981

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.601

High

547766

NHP6A
Non-histone chromosomal protein 6A

2

7

Small-scale

0.601

High

380987

H2B1
Histone H2B.1

2

5

High-throughput

0.571

High

678312

SPT10
Protein SPT10

2

1

High-throughput

0.571

High

678358

H2AZ
Histone H2A.Z

2

3

High-throughput

0.571

High

526043

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

678343

POB3
FACT complex subunit POB3

2

0

High-throughput

0.547

High

678336

ABF2
ARS-binding factor 2, mitochondrial

1

8

High-throughput

0.536

High

678354

PKH2
Serine/threonine-protein kinase PKH2

1

1

High-throughput

0.501

High

678316

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.489

High

678328

RIM15
Serine/threonine-protein kinase RIM15

1

0

High-throughput

0.480

High

678340

STE20
Serine/threonine-protein kinase STE20

1

0

Small-scale

0.480

High

381425

H2B2
Histone H2B.2

1

5

High-throughput

0.479

High

448928

TOP2
DNA topoisomerase 2

1

2

High-throughput

0.479

High

678297

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

678299

BTAF1
TATA-binding protein-associated factor MOT1

1

20

Small-scale

0.479

High

678300

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

678307

CHD1
Chromo domain-containing protein 1

1

10

High-throughput

0.479

High

678310

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

678311

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

678313

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.479

High

678314

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.479

High

678321

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.479

High

678353

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

678357

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

678359

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

678326

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

448287

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

561425

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

678303

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

678319

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

678327

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

678342

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

678347

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

678351

SGO1
Shugoshin

1

0

High-throughput

0.458

High

678352

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.458

High

448140

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

481506

HSP73
Heat shock protein SSA3

1

3

High-throughput

0.445

High

488923

SWI6
Regulatory protein SWI6

1

3

High-throughput

0.445

High

523200

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

645591

AFT1
Iron-regulated transcriptional activator AFT1

1

1

High-throughput

0.445

High

671499

SWI4
Regulatory protein SWI4

1

4

High-throughput

0.445

High

678296

RSC6
Chromatin structure-remodeling complex protein RSC6

1

5

High-throughput

0.445

High

678301

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

678302

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

1

High-throughput

0.445

High

678305

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

678315

SET3
SET domain-containing protein 3

1

2

High-throughput

0.445

High

678322

MBP1
Transcription factor MBP1

1

3

High-throughput

0.445

High

678337

HOS3
Histone deacetylase HOS3

1

1

High-throughput

0.445

High

678339

GCN5
Histone acetyltransferase GCN5

1

14

High-throughput

0.445

High

678345

SWR1
Helicase SWR1

1

20

High-throughput

0.445

High

678356

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.445

High

678325

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.438

High

548752

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

590550

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

649918

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

678323

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

678331

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.426

High

678341

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

678320

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.282

High

678308

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.261

Low

678317

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.261

Low

678304

SPS19
Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.238

Low

444832

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.232

Low

626614

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

678298

OAC1
Mitochondrial oxaloacetate transport protein

1

0

High-throughput

0.232

Low

678330

ERJ5
ER-localized J domain-containing protein 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025