HitPredict

Interactor 1: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 780
+	Hs
		681439 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		681437 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		681440 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		681438 DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		243399 DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1274015 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1042259 DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		636327 DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042743 DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Zm
		26325 K7UU30_MAIZE (6-346): 1.71e-55: 187: 39.21		A0A1D6J2B8_MAIZE (8-780): 0: 702: 23.20