HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 36931259, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 474
+	Hs
		909603 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		927085 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		253248 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI21B_HUMAN (35-374): 2.35e-29: 124: 19.73
+	Mm
		910349 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		KI21B_MOUSE (1-374): 6.9e-29: 122: 19.31
+	Hs
		927164 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKG_HUMAN (1-433): 4.02e-31: 129: 15.49
+	Hs
		909555 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		683340 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		927035 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (2-406): 4.45e-12: 70.8: 7.14
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07
+	Hs
		910111 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DAPLE_HUMAN (52-339): 4.11e-09: 61.2: 16.88
+	Mm
		926886 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MY18A_MOUSE (53-345): 7.76e-11: 67: 14.75
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39
+	Hs
		683774 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DAPLE_HUMAN (52-339): 4.11e-09: 61.2: 16.88
+	Mm
		926889 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		PLEC_MOUSE (48-346): 2.11e-10: 65.4: 14.46
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07
+	Hs
		502907 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH3_HUMAN (48-349): 1.75e-09: 62.3: 11.88
+	Hs
		927068 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (3-404): 7.14e-09: 60.4: 10.67