HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: RFIP2 (Q7L804)
Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11)
Gene: RAB11FIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.50	0.654

Property	Details
Experiments	33961781, 35271311, 36931259, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 512
+	Hs
		909736 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RFIP2_HUMAN (1-512): 1.78e-156: 457: 100.00
+	Hs
		927218 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RFIP2_HUMAN (1-512): 1.78e-156: 457: 100.00
+	Mm
		103331 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		RFIP2_MOUSE (1-512): 1.83e-153: 449: 93.36
+	Hs
		566348 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		KPCA_HUMAN (14-226): 8.32e-45: 169: 14.54
+	Hs
		397155 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KPCG_HUMAN (15-226): 3.11e-38: 150: 16.22
+	Dm
		955045 1433E_DROME (3-245): 4.63e-144: 405: 64.90		Q9VWS3_DROME (10-173): 6.11e-38: 150: 41.32
+	Hs
		909981 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RFIP5_HUMAN (141-504): 7.27e-33: 134: 16.41
+	Hs
		683679 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RFIP5_HUMAN (141-504): 7.27e-33: 134: 16.41
+	Mm
		926854 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		RFIP5_MOUSE (143-504): 1.46e-32: 133: 16.84
+	Hs
		927480 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RFIP5_HUMAN (141-504): 7.27e-33: 134: 16.41
+	Hs
		909704 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		566293 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		KPCA_HUMAN (14-226): 8.32e-45: 169: 14.54
+	Hs
		683468 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		927190 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Mm
		926842 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		Q8C8C0_MOUSE (14-231): 4.9e-21: 98.7: 18.39
+	Hs
		48275 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ESYT2_HUMAN (1-122): 2.96e-17: 87.4: 20.93
+	Hs
		647022 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		RFIP1_HUMAN (125-508): 9.75e-30: 126: 18.49
+	Hs
		909754 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77
+	Hs
		683503 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77
+	Hs
		927239 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RIMS1_HUMAN (13-127): 8.22e-13: 73.5: 23.77