HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: Q9UQC1 (Q9UQC1)
Heat shock protein 72
Gene: HSP70-1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 151
+	Hs
		683392 IKBA_HUMAN (1-317): 6.84e-85: 259: 100.00		HS71L_HUMAN (1-150): 2.62e-76: 240: 91.33
+	Hs
		536537 IKBA_HUMAN (1-317): 6.84e-85: 259: 100.00		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Hs
		761454 ANKK1_HUMAN (3-302): 6.84e-78: 254: 21.67		HS71L_HUMAN (1-150): 2.62e-76: 240: 91.33
+	Mm
		989297 IKBA_MOUSE (1-317): 9.27e-79: 244: 91.17		HSP7C_MOUSE (1-150): 6.84e-76: 239: 87.33
+	Hs
		127798 IKBE_HUMAN (3-315): 1.29e-74: 239: 32.10		Q9UQC1_HUMAN (1-151): 8.58e-83: 241: 100.00
+	Hs
		127766 IKBE_HUMAN (3-315): 1.29e-74: 239: 32.10		HS71L_HUMAN (1-150): 2.62e-76: 240: 91.33
+	Hs
		127758 IKBE_HUMAN (3-315): 1.29e-74: 239: 32.10		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Mm
		681984 NFKB1_MOUSE (70-302): 5.49e-66: 224: 38.98		HS71A_MOUSE (1-150): 9.82e-78: 243: 95.33
+	Dr
		1239763 MIB1_DANRE (1-299): 1.47e-66: 226: 24.63		Q6NYR4_DANRE (1-150): 3.96e-75: 237: 87.33
+	Hs
		600792 NFKB2_HUMAN (68-294): 6.69e-64: 218: 34.32		HSP76_HUMAN (1-150): 3.21e-78: 245: 85.33
+	Hs
		1026787 NFKB2_HUMAN (68-294): 6.69e-64: 218: 34.32		Q9UQC1_HUMAN (1-151): 8.58e-83: 241: 100.00
+	Hs
		761371 NFKB2_HUMAN (68-294): 6.69e-64: 218: 34.32		HS71L_HUMAN (1-150): 2.62e-76: 240: 91.33
+	Hs
		536980 NFKB2_HUMAN (68-294): 6.69e-64: 218: 34.32		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Hs
		516164 ANK2_HUMAN (118-312): 7.83e-41: 153: 23.86		HS71A_HUMAN (1-150): 1.19e-77: 243: 100.00
+	Hs
		536991 ANK2_HUMAN (118-312): 7.83e-41: 153: 23.86		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Hs
		600783 RIPK4_HUMAN (136-316): 1.51e-32: 129: 24.31		HSP76_HUMAN (1-150): 3.21e-78: 245: 85.33
+	Hs
		600935 Q9H4D1_HUMAN (136-316): 3.11e-32: 128: 24.31		HSP76_HUMAN (1-150): 3.21e-78: 245: 85.33
+	Hs
		536849 RIPK4_HUMAN (136-316): 1.51e-32: 129: 24.31		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Hs
		537908 Q9H4D1_HUMAN (136-316): 3.11e-32: 128: 24.31		HSP7C_HUMAN (1-150): 6.84e-76: 239: 87.33
+	Hs
		600732 BCL3_HUMAN (26-234): 3.02e-29: 118: 24.76		HSP76_HUMAN (1-150): 3.21e-78: 245: 85.33