Protein: IKBA
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha)

Gene: IKBA, Nfkbia
Organism: Mus musculus
Interactions: 28
UniProt ID: Q9Z1E3

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046000

TF65
Transcription factor p65

21

20

Small-scale

0.986

High

312522

NEMO
NF-kappa-B essential modulator

5

20

Small-scale

0.917

High

1190513

FBW1A
F-box/WD repeat-containing protein 1A

4

20

Small-scale

0.893

High

312175

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

4

20

Small-scale

0.885

High

682002

NFKB1
Nuclear factor NF-kappa-B p105 subunit

3

18

Small-scale

0.827

High

1048826

RELB
Transcription factor RelB

2

20

Small-scale

0.767

High

1210440

FBW1B
F-box/WD repeat-containing protein 11

1

20

Small-scale

0.647

High

582540

REL
Proto-oncogene c-Rel

1

20

Small-scale

0.646

High

382525

P53
Cellular tumor antigen p53

1

10

High-throughput

0.621

High

1440913

SPAG6
Sperm-associated antigen 6

1

6

High-throughput

0.621

High

980679

H4
Histone H4

1

3

Small-scale

0.618

High

1197935

TRI67
Tripartite motif-containing protein 67

1

20

Small-scale

0.618

High

1203413

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

3

Small-scale

0.618

High

1224138

IRAK1
Interleukin-1 receptor-associated kinase 1

1

5

Small-scale

0.618

High

1490172

NFAT5
Nuclear factor of activated T-cells 5

1

20

Small-scale

0.618

High

484848

HXA9
Homeobox protein Hox-A9

1

19

Small-scale

0.561

High

1423582

FBX32
F-box only protein 32

1

1

Small-scale

0.561

High

1190406

Q3UKX1
Protein arginine N-methyltransferase 2

1

3

Small-scale

0.553

High

1222281

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

7

Small-scale

0.553

High

313131

HDAC3
Histone deacetylase 3

1

18

Small-scale

0.479

High

470407

IL6
Interleukin-6

1

3

Small-scale

0.479

High

723161

CCL5
C-C motif chemokine 5

1

9

Small-scale

0.479

High

771402

HES1
Transcription factor HES-1

1

1

Small-scale

0.479

High

871155

VDR
Vitamin D3 receptor

1

17

Small-scale

0.479

High

989297

HSP7C
Heat shock cognate 71 kDa protein

1

20

Small-scale

0.479

High

1221468

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

16

Small-scale

0.479

High

1281989

SUZ12
Polycomb protein Suz12

1

2

Small-scale

0.479

High

1455812

TLR2
Toll-like receptor 2

1

1

Small-scale

0.445

High


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Last updated: 11Aug2025