HitPredict

Interactor 1: PC (P26017)
Polycomb group protein Pc (Protein polycomb)
Gene: PC

Interactor 2: H2A (P84051)
Histone H2A
Gene: His2A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23320494
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~Histone
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005700 - polytene chromosome GO:0005704 - polytene chromosome band GO:0031507 - heterochromatin formation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Dm			1 124
+	Hs
		338888 CBX6_HUMAN (17-378): 1.72e-66: 218: 20.46		H2A2B_HUMAN (1-122): 1.38e-62: 188: 90.24
+	Hs
		338753 CBX6_HUMAN (17-378): 1.72e-66: 218: 20.46		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		1413561 CBX8_HUMAN (17-380): 4.13e-60: 201: 20.15		H2AJ_HUMAN (1-123): 2.22e-62: 188: 90.32
+	Hs
		419214 CBX8_HUMAN (17-380): 4.13e-60: 201: 20.15		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		591892 CDYL_HUMAN (5-282): 8.7e-54: 189: 15.73		H2AX_HUMAN (1-120): 6.87e-62: 187: 90.91
+	Hs
		1162928 CDYL_HUMAN (5-282): 8.7e-54: 189: 15.73		H2A2C_HUMAN (1-122): 1.63e-61: 185: 89.43
+	Hs
		419279 CDYL_HUMAN (5-282): 8.7e-54: 189: 15.73		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		502596 CDYL_HUMAN (5-282): 8.7e-54: 189: 15.73		H2A1_HUMAN (1-122): 3.29e-61: 185: 89.43
+	Hs
		129635 CBX4_HUMAN (17-338): 4.29e-46: 167: 18.53		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		419293 CDY2_HUMAN (22-235): 8.27e-43: 158: 15.09		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		418988 CBX2_HUMAN (16-333): 1.48e-38: 146: 16.52		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		216481 SUV91_HUMAN (26-165): 4.79e-32: 127: 13.99		H2A2B_HUMAN (1-122): 1.38e-62: 188: 90.24
+	Hs
		216447 SUV91_HUMAN (26-165): 4.79e-32: 127: 13.99		H2A2C_HUMAN (1-122): 1.63e-61: 185: 89.43
+	Hs
		591629 CBX3_HUMAN (6-87): 1.2e-28: 112: 30.49		H2AX_HUMAN (1-120): 6.87e-62: 187: 90.91
+	Hs
		634022 CBX3_HUMAN (6-87): 1.2e-28: 112: 30.49		H2A1D_HUMAN (1-122): 3.18e-61: 185: 88.62
+	Hs
		591519 CBX5_HUMAN (7-124): 8.42e-26: 104: 23.73		H2AX_HUMAN (1-120): 6.87e-62: 187: 90.91
+	Hs
		853320 CBX5_HUMAN (7-124): 8.42e-26: 104: 23.73		H2A3_HUMAN (1-122): 2.1e-61: 185: 89.43
+	Hs
		418940 CBX1_HUMAN (32-120): 1.62e-23: 98.5: 31.46		H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62
+	Hs
		502320 CBX1_HUMAN (32-120): 1.62e-23: 98.5: 31.46		H2A1_HUMAN (1-122): 3.29e-61: 185: 89.43
+	Hs
		634019 CBX1_HUMAN (32-120): 1.62e-23: 98.5: 31.46		H2A1D_HUMAN (1-122): 3.18e-61: 185: 88.62