HitPredict

Interactor 1: PC (P26017)
Polycomb group protein Pc (Protein polycomb)
Gene: PC

Interactor 2: RING1 (Q9VB08)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RING1) (Sex comb extra protein) (dRING protein) (dRING1)
Gene: Sce

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 18923078, 25415640, 22491092, 18981224, 15147763, 21415365, 26063573, 25468754, 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CBX7_C~RAWUL
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006357 - regulation of transcription by RNA polymerase II
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 390
Dm

1 435
+ Dm
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025