HitPredict

Interactor 1: RADI (P26043)
Radixin (ESP10)
Gene: Rdx

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	10806479
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030027 - lamellipodium GO:0045792 - negative regulation of cell size
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 583 Mm			1 1161
+	Mm
		683944 EZRI_MOUSE (1-583): 7.77e-165: 484: 75.94		TSC1_MOUSE (1-1161): 0: 753: 100.00
+	Hs
		582904 EZRI_HUMAN (1-583): 2.83e-165: 485: 76.28		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Hs
		683874 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Mm
		683952 MOES_MOUSE (1-583): 3.9e-160: 471: 80.96		TSC1_MOUSE (1-1161): 0: 753: 100.00
+	Hs
		767284 MERL_HUMAN (2-583): 3.59e-156: 462: 45.47		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Hs
		1361423 MYLIP_HUMAN (9-241): 2.24e-28: 120: 32.91		TSC1_HUMAN (1-1161): 0: 749: 86.98
+	Hs
		1292915 MYLIP_HUMAN (9-241): 2.24e-28: 120: 32.91		Q86WV8_HUMAN (1-343): 9.33e-180: 532: 91.25
+	Hs
		156914 EZRI_HUMAN (1-583): 2.83e-165: 485: 76.28		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Rn
		3026 MERL_RAT (2-567): 1.01e-148: 442: 45.52		A0A0G2JX94_RAT (380-1062): 4.55e-33: 141: 13.12
+	Hs
		582832 EZRI_HUMAN (1-583): 2.83e-165: 485: 76.28		CCD18_HUMAN (311-1160): 1.62e-18: 94.2: 10.53
+	Hs
		157015 MERL_HUMAN (2-583): 3.59e-156: 462: 45.47		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Hs
		583015 EZRI_HUMAN (1-583): 2.83e-165: 485: 76.28		MYH13_HUMAN (288-863): 3.56e-13: 76.5: 8.05
+	Hs
		767434 RADI_HUMAN (1-583): 3.01e-168: 492: 98.46		SLMAP_HUMAN (681-959): 6.74e-09: 62.5: 20.13
+	Hs
		683785 MOES_HUMAN (1-583): 1.81e-161: 475: 80.79		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22
+	Hs
		1433661 E41L1_HUMAN (3-499): 5.99e-117: 369: 22.01		MYH4_HUMAN (411-1154): 2.23e-26: 119: 7.82
+	Hs
		538891 EPB41_HUMAN (3-555): 2.47e-127: 396: 17.66		MYH9_HUMAN (773-1161): 6.5e-11: 69.1: 10.22
+	Hs
		538892 EPB41_HUMAN (3-555): 2.47e-127: 396: 17.66		MYH10_HUMAN (617-910): 7.88e-10: 65.7: 13.27
+	Hs
		157557 FRMD5_HUMAN (1-484): 1.31e-112: 349: 21.56		CTRO_HUMAN (681-1159): 2.61e-23: 109: 11.20
+	Dm
		1466570 EPB41_DROME (3-394): 4.7e-108: 357: 24.44		Q9VCC9_DROME (772-1075): 4.3e-11: 69.5: 8.60