HitPredict

Interactor 1: GP183 (P32249)
G-protein coupled receptor 183 (Epstein-Barr virus-induced G-protein coupled receptor 2) (EBI2) (EBV-induced G-protein coupled receptor 2) (hEBI2)
Gene: GPR183

Interactor 2: EI2BE (Q13144)
Translation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene: EIF2B5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 721
+	Hs
		1025623 GPR17_HUMAN (25-343): 3.23e-86: 266: 26.96		EI2BE_HUMAN (14-711): 0: 634: 100.00
+	Hs
		666309 NK3R_HUMAN (10-352): 1.07e-69: 227: 19.31		EI2BE_HUMAN (14-711): 0: 634: 100.00
+	Hs
		1025631 P2RY6_HUMAN (31-325): 3.09e-34: 130: 27.18		EI2BE_HUMAN (14-711): 0: 634: 100.00
+	Hs
		1031087 GPR17_HUMAN (25-343): 3.23e-86: 266: 26.96		EI2BG_HUMAN (42-451): 6.82e-86: 279: 18.28
+	Hs
		686822 GP183_HUMAN (1-361): 2.26e-84: 261: 100.00		EI2BG_HUMAN (42-451): 6.82e-86: 279: 18.28
+	Hs
		1067624 P2RY6_HUMAN (31-325): 3.09e-34: 130: 27.18		EI2BG_HUMAN (42-451): 6.82e-86: 279: 18.28
+	Hs
		1031128 GPR17_HUMAN (25-343): 3.23e-86: 266: 26.96		5MP1_HUMAN (594-713): 7.45e-13: 72.9: 18.33
+	Hs
		1030983 GPR17_HUMAN (25-343): 3.23e-86: 266: 26.96		5MP2_HUMAN (554-712): 3.61e-12: 71: 20.63
+	Hs
		686827 GP183_HUMAN (1-361): 2.26e-84: 261: 100.00		5MP1_HUMAN (594-713): 7.45e-13: 72.9: 18.33
+	Hs
		1067525 P2RY6_HUMAN (31-325): 3.09e-34: 130: 27.18		5MP2_HUMAN (554-712): 3.61e-12: 71: 20.63