HitPredict

Interactor 1: NKG2D (P26718)
NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)
Gene: KLRK1

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0030246 - carbohydrate binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 592
+	Hs
		698745 COL12_HUMAN (84-213): 1.13e-43: 157: 19.86		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		699251 CLC4E_HUMAN (25-213): 1.26e-40: 139: 19.90		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		688655 NKG2C_HUMAN (22-215): 6.11e-40: 138: 20.71		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		698710 CL12B_HUMAN (82-215): 1.14e-39: 138: 33.80		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		688528 NKG2A_HUMAN (22-215): 1.39e-39: 137: 22.56		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		455902 ASGR1_HUMAN (79-215): 5.24e-38: 134: 24.67		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		698624 KLRD1_HUMAN (57-216): 1.17e-37: 131: 27.65		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		698790 CLC4G_HUMAN (80-214): 1.73e-36: 131: 24.14		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		698953 CLC2B_HUMAN (57-214): 2.89e-37: 128: 27.50		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		170796 COL12_HUMAN (84-213): 1.13e-43: 157: 19.86		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		171018 CLC4E_HUMAN (25-213): 1.26e-40: 139: 19.90		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170667 NKG2C_HUMAN (22-215): 6.11e-40: 138: 20.71		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170782 CL12B_HUMAN (82-215): 1.14e-39: 138: 33.80		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170666 NKG2A_HUMAN (22-215): 1.39e-39: 137: 22.56		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170896 CLC4D_HUMAN (42-212): 4.08e-38: 132: 16.75		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170747 KLRD1_HUMAN (57-216): 1.17e-37: 131: 27.65		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170897 CLC2B_HUMAN (57-214): 2.89e-37: 128: 27.50		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		698070 CLC4E_HUMAN (25-213): 1.26e-40: 139: 19.90		CALR_HUMAN (67-470): 1.2e-141: 418: 38.33
+	Hs
		688527 NKG2A_HUMAN (22-215): 1.39e-39: 137: 22.56		CALR_HUMAN (67-470): 1.2e-141: 418: 38.33
+	Hs
		697970 CLC4D_HUMAN (42-212): 4.08e-38: 132: 16.75		CALR_HUMAN (67-470): 1.2e-141: 418: 38.33