HitPredict

Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 618
+	Hs
		787134 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		787135 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		581036 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Mm
		1050619 TGFR2_MOUSE (54-493): 2.6e-120: 366: 35.19		RAC2_MOUSE (3-183): 1.62e-79: 251: 26.67
+	Hs
		788880 TGFR2_HUMAN (28-493): 8.85e-123: 372: 33.79		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		953436 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		955150 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		1015425 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		788888 TGFR2_HUMAN (28-493): 8.85e-123: 372: 33.79		RB11A_HUMAN (5-202): 4.27e-72: 232: 19.00
+	Hs
		988352 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		601176 AVR2A_HUMAN (1-513): 3.38e-154: 451: 100.00		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26
+	Hs
		787137 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		787136 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		466130 BMR1A_HUMAN (59-488): 2.94e-128: 385: 33.41		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		977996 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		962034 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		1118389 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOF_HUMAN (2-167): 3.39e-11: 65.1: 26.67
+	Hs
		466243 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126587 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		601280 BMPR2_HUMAN (5-505): 8.65e-116: 367: 32.96		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26