HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: DLG5 (Q8TDM6)
Disks large homolog 5 (Discs large protein P-dlg) (Placenta and prostate DLG)
Gene: DLG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1919
+	Hs
		971813 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DLG5_HUMAN (1-1919): 0: 879: 100.00
+	Hs
		990530 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		DLG5_HUMAN (1-1919): 0: 879: 100.00
+	Hs
		730080 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		DLG5_HUMAN (1-1919): 0: 879: 100.00
+	Mm
		972235 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44
+	Mm
		989977 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44
+	Mm
		1223711 1433B_MOUSE (1-242): 2.85e-124: 354: 80.99		DLG4_MOUSE (1177-1916): 1.49e-154: 495: 19.44
+	Dm
		723780 1433E_DROME (2-242): 6.8e-143: 401: 65.02		DLG1_DROME (1243-1578): 5.86e-22: 105: 13.76
+	Dm
		709523 1433Z_DROME (1-245): 3.69e-141: 397: 77.14		DLG1_DROME (1243-1578): 5.86e-22: 105: 13.76
+	Hs
		971450 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		CGNL1_HUMAN (145-628): 2.89e-10: 67.8: 21.72
+	Hs
		972097 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06
+	Hs
		690946 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		CGNL1_HUMAN (145-628): 2.89e-10: 67.8: 21.72
+	Hs
		990150 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		CGNL1_HUMAN (145-628): 2.89e-10: 67.8: 21.72
+	Hs
		691515 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06
+	Hs
		690935 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81
+	Hs
		990834 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06
+	Hs
		990136 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81
+	Hs
		729781 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		CGNL1_HUMAN (145-628): 2.89e-10: 67.8: 21.72
+	Hs
		730325 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		ZO2_HUMAN (1347-1499): 3.2e-09: 64.3: 15.06
+	Hs
		729772 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81
+	Hs
		730535 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		ZO1_HUMAN (698-816): 5.89e-09: 63.8: 16.81