HitPredict

Interactor 1: LEF1 (P27782)
Lymphoid enhancer-binding factor 1 (LEF-1)
Gene: LEF1

Interactor 2: SOX17 (Q61473)
Transcription factor SOX-17
Gene: SOX17

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17875931
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
and 10 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 397
Mm

1 419
+ Hs
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+ Dm
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+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025