Interactor 1: MRE11 (P32829)
Double-strand break repair protein MRE11 (EC 3.1.-.-)
Gene: MRE11

Interactor 2: MRE11 (P32829)
Double-strand break repair protein MRE11 (EC 3.1.-.-)
Gene: MRE11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.933

The method score is based on:

Property Details
Experiments 23122649, 10219078, 7789757, 9799249, 29420790, 22705791
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos, Metallophos~Mre11_DNA_bind
Common GO terms GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0000727 - double-strand break repair via break-induced replication
GO:0000729 - DNA double-strand break processing
and 31 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 692
Sc

1 692
+ Hs
+ Mm
+ Sp
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024