Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1
Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.39 | 1.00 | 0.625 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25284480 |
| Identification Methods | anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025