HitPredict

Interactor 1: PSB9 (P28065)
Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein)
Gene: PSMB9

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	26186194, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Hs			1 329
+	Hs
		700768 PSA5_HUMAN (5-219): 4.73e-79: 238: 17.90		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		700491 PSB8_HUMAN (10-219): 6.31e-75: 229: 29.38		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		701253 PSB5_HUMAN (2-219): 3.15e-74: 226: 27.15		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		1404137 PSB7_HUMAN (10-205): 3.87e-72: 222: 27.04		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		681750 PSA4_HUMAN (5-217): 3.82e-72: 221: 15.49		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		681248 PSA2_HUMAN (6-217): 1.09e-71: 219: 14.48		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		701100 PSB6_HUMAN (13-216): 8.81e-72: 219: 61.46		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Sp
		1462954 PSA5_SCHPO (5-219): 1.4e-78: 237: 19.57		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		1068363 PSA3_SCHPO (5-219): 9.54e-75: 227: 15.28		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		1068646 PSB2_SCHPO (10-204): 3.43e-73: 224: 26.67		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		207228 PSB1_SCHPO (13-211): 1.87e-72: 221: 44.50		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Dm
		47748 A0AQH0_DROME (7-212): 1.17e-77: 234: 51.21		UCHL_DROME (8-228): 1.94e-79: 243: 24.78
+	Dm
		762574 PSA5_DROME (5-218): 2.7e-76: 231: 16.96		UCHL_DROME (8-228): 1.94e-79: 243: 24.78
+	Dm
		762550 Q7K148_DROME (17-217): 3.69e-72: 222: 28.71		UCHL_DROME (8-228): 1.94e-79: 243: 24.78
+	Hs
		488405 PSA4_HUMAN (5-217): 3.82e-72: 221: 15.49		UCHL1_HUMAN (10-226): 4.55e-75: 231: 22.22
+	Hs
		700698 PSA5_HUMAN (5-219): 4.73e-79: 238: 17.90		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		1364535 PSB7_HUMAN (10-205): 3.87e-72: 222: 27.04		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		681693 PSA4_HUMAN (5-217): 3.82e-72: 221: 15.49		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		681207 PSA2_HUMAN (6-217): 1.09e-71: 219: 14.48		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		701063 PSB6_HUMAN (13-216): 8.81e-72: 219: 61.46		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29