HitPredict

Interactor 1: TMOD1 (P28289)
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Gene: TMOD1

Interactor 2: PKHG6 (Q3KR16)
Pleckstrin homology domain-containing family G member 6 (PH domain-containing family G member 6) (Myosin-interacting guanine nucleotide exchange factor) (MyoGEF)
Gene: PLEKHG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 790
+	Hs
		1186393 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		PKHG6_HUMAN (1-790): 1.03e-180: 539: 100.00
+	Hs
		584480 TMOD1_HUMAN (1-359): 1.53e-167: 473: 100.00		VAV_HUMAN (99-690): 5.99e-87: 295: 15.02
+	Hs
		702028 TMOD1_HUMAN (1-359): 1.53e-167: 473: 100.00		Q96D37_HUMAN (99-690): 1.41e-87: 295: 15.02
+	Hs
		177364 TMOD1_HUMAN (1-359): 1.53e-167: 473: 100.00		ARHGB_HUMAN (22-750): 1.28e-81: 287: 17.48
+	Hs
		1207815 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		Q5JYA6_HUMAN (45-746): 6.78e-87: 302: 15.93
+	Hs
		1453573 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		PKHG1_HUMAN (45-746): 6.78e-87: 302: 15.93
+	Hs
		1436514 TMOD3_HUMAN (1-345): 1.44e-153: 437: 62.14		ECT2_HUMAN (77-645): 5.33e-81: 280: 19.26
+	Hs
		1387019 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		Q96D37_HUMAN (99-690): 1.41e-87: 295: 15.02
+	Hs
		584592 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		VAV_HUMAN (99-690): 5.99e-87: 295: 15.02
+	Hs
		177409 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		ARHGB_HUMAN (22-750): 1.28e-81: 287: 17.48
+	Hs
		1436518 TMOD2_HUMAN (1-345): 8.94e-146: 417: 59.54		ECT2_HUMAN (77-645): 5.33e-81: 280: 19.26