Interactor 1: PTPRM (P28827)
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
Gene: PTPRM
Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 36976175 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ephrin_lbd~fn3, fn3~fn3, PK_Tyr_Ser-Thr~fn3, fn3~ig, Y_phosphatase~fn3, PK_Tyr_Ser-Thr~Y_phosphatase, SAM_1~Y_phosphatase |
| Common GO terms | GO:0005886 - plasma membrane GO:0016525 - negative regulation of angiogenesis GO:0030027 - lamellipodium GO:0045296 - cadherin binding |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
