Interactor 1: NTF4 (P34130)
Neurotrophin-4 (NT-4) (Neurotrophin-5) (NT-5) (Neutrophic factor 4)
Gene: NTF4

Interactor 2: NTRK2 (Q16620)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)
Gene: NTRK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 29997244, 11855816, 11738045
Identification Methods fluorescent resonance energy transfer, pull down, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~NGF
Common GO terms GO:0030424 - axon
GO:0030425 - dendrite
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0042490 - mechanoreceptor differentiation
GO:0043524 - negative regulation of neuron apoptotic process
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 210
Hs

1 822
+ Hs
+ Mm
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+ Mm
+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024