HitPredict

Interactor 1: IF4B (P34167)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: TIF3

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002181 - cytoplasmic translation GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 436 Sc			1 613
+	Sc
		510803 IF4B_YEAST (1-436): 7.08e-121: 360: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		648382 NSR1_YEAST (90-196): 7.89e-12: 68.5: 12.96		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510467 NSR1_YEAST (90-196): 7.89e-12: 68.5: 12.96		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		564007 IF4B_HUMAN (11-426): 3.29e-47: 173: 17.11		HSP76_HUMAN (3-612): 0: 898: 58.82
+	Hs
		503453 IF4B_HUMAN (11-426): 3.29e-47: 173: 17.11		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		450001 IF4B_YEAST (1-436): 7.08e-121: 360: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66