HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	18448430
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~SH3_1, Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 968 Hs			1 1128
+	Hs
		587647 NFKB1_HUMAN (1-968): 0: 796: 100.00		IASPP_HUMAN (416-1127): 1.13e-53: 204: 21.65
+	Hs
		587690 NFKB1_HUMAN (1-968): 0: 796: 100.00		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		978748 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		276140 NFKB1_HUMAN (1-968): 0: 796: 100.00		PSD10_HUMAN (988-1128): 3e-43: 159: 16.77
+	Hs
		587628 NFKB1_HUMAN (1-968): 0: 796: 100.00		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		978823 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		IASPP_HUMAN (416-1127): 1.13e-53: 204: 21.65
+	Hs
		978869 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		276172 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		PSD10_HUMAN (988-1128): 3e-43: 159: 16.77
+	Hs
		167036 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78
+	Hs
		964519 RELB_HUMAN (30-459): 1.19e-121: 384: 33.10		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		161473 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Mm
		103591 ANK3_MOUSE (381-967): 1e-99: 346: 14.24		ANK3_MOUSE (681-1011): 3.26e-23: 109: 12.69
+	Hs
		639798 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		965154 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		883487 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		166913 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78
+	Mm
		103608 ANK2_MOUSE (63-670): 1.29e-71: 262: 12.37		ANK3_MOUSE (681-1011): 3.26e-23: 109: 12.69
+	Hs
		862028 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		DAPK1_HUMAN (791-1011): 1.31e-20: 100: 13.12
+	Hs
		225123 ANK1_HUMAN (539-967): 7.32e-78: 281: 16.84		MYPT2_HUMAN (947-1035): 1.24e-11: 71.4: 33.71
+	Hs
		225134 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		MYPT2_HUMAN (947-1035): 1.24e-11: 71.4: 33.71