HitPredict

Interactor 1: EDE1 (P34216)
EH domain-containing and endocytosis protein 1 (Bud site selection protein 15)
Gene: EDE1

Interactor 2: AP2A (P38065)
AP-2 complex subunit alpha (Alpha-adaptin) (Clathrin assembly protein complex 2 alpha large chain) (Clathrin assembly protein large alpha chain)
Gene: APL3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37766990
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005935 - cellular bud neck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1381 Sc			1 1025
+	Hs
		321498 MYH9_HUMAN (562-1329): 1.43e-32: 140: 9.13		AP2A1_HUMAN (11-1023): 0: 676: 21.52
+	Hs
		321615 REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19		AP2A1_HUMAN (11-1023): 0: 676: 21.52
+	Hs
		302193 REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19		AP2A2_HUMAN (11-1023): 0: 673: 22.10
+	Hs
		321552 ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27		AP2A1_HUMAN (11-1023): 0: 676: 21.52
+	Hs
		302157 ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27		AP2A2_HUMAN (11-1023): 0: 673: 22.10
+	Rn
		88768 ITSN1_RAT (719-1084): 1.45e-14: 81.5: 12.86		D3ZUY8_RAT (11-1023): 0: 678: 22.27
+	Hs
		321661 EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38		AP2A1_HUMAN (11-1023): 0: 676: 21.52
+	Hs
		302221 EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38		AP2A2_HUMAN (11-1023): 0: 673: 22.10
+	Dm
		112642 M9NDL7_DROME (2-624): 6.22e-16: 85.7: 9.79		AP2A_DROME (12-1023): 0: 653: 23.00
+	Ce
		1094946 Q9U2T9_CAEEL (8-269): 1.42e-19: 97.7: 17.53		Q22601_CAEEL (13-1023): 0: 634: 21.69
+	Hs
		724758 MYH9_HUMAN (562-1329): 1.43e-32: 140: 9.13		AP2B1_HUMAN (43-1018): 0: 558: 12.57
+	Hs
		925970 REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19		AP2B1_HUMAN (43-1018): 0: 558: 12.57
+	Hs
		1014062 REPS1_HUMAN (2-488): 7.74e-23: 107: 13.19		AP1B1_HUMAN (43-1017): 8.29e-179: 547: 11.88
+	Hs
		925876 ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27		AP2B1_HUMAN (43-1018): 0: 558: 12.57
+	Hs
		926031 ITSN2_HUMAN (825-1202): 1.33e-15: 85: 9.44		AP2B1_HUMAN (43-1018): 0: 558: 12.57
+	Rn
		923861 ITSN1_RAT (719-1084): 1.45e-14: 81.5: 12.86		AP2B1_RAT (43-1018): 0: 558: 12.57
+	Hs
		926038 EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38		AP2B1_HUMAN (43-1018): 0: 558: 12.57
+	Hs
		1014017 ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27		AP1B1_HUMAN (43-1017): 8.29e-179: 547: 11.88
+	Hs
		1014096 ITSN2_HUMAN (825-1202): 1.33e-15: 85: 9.44		AP1B1_HUMAN (43-1017): 8.29e-179: 547: 11.88
+	Dm
		112643 M9NDL7_DROME (2-624): 6.22e-16: 85.7: 9.79		Q24253_DROME (43-1015): 3.2e-166: 513: 11.85