HitPredict

Interactor 1: UBC8 (P35131)
Ubiquitin-conjugating enzyme E2 8 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 8) (UBCAT4A) (Ubiquitin carrier protein 8) (Ubiquitin-conjugating enzyme E2-17 kDa 8) (Ubiquitin-protein ligase 8)
Gene: UBC8

Interactor 2: CHIP (Q9SRS9)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Carboxyl terminus of HSC70-interacting protein) (AtCHIP) (Plant U-box protein 61) (RING-type E3 ubiquitin transferase CHIP) (U-box domain-containing protein 61)
Gene: CHIP

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	16640601
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	U-box~UQ_con
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 148 At			1 278
+	At
		715145 UBC9_ARATH (1-148): 5.79e-83: 241: 95.95		CHIP_ARATH (1-278): 4.63e-61: 196: 100.00
+	At
		715154 UBC10_ARATH (1-148): 6.12e-83: 241: 95.95		CHIP_ARATH (1-278): 4.63e-61: 196: 100.00
+	Hs
		1357485 UB2D4_HUMAN (1-147): 1.18e-82: 241: 80.27		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		849489 UB2D1_HUMAN (1-147): 9.91e-82: 238: 76.19		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		919907 UB2D2_HUMAN (1-147): 1.55e-81: 238: 80.27		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		895956 UB2D3_HUMAN (1-147): 1.89e-80: 235: 79.59		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		1297379 UB2E2_HUMAN (2-146): 7.81e-74: 220: 62.76		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		1282365 UB2E3_HUMAN (2-146): 2.21e-73: 219: 62.07		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Hs
		851908 UB2E1_HUMAN (2-146): 5.46e-72: 215: 62.76		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Ce
		105587 UBC2_CAEEL (1-147): 1.52e-81: 238: 79.59		G5ECY6_CAEEL (10-274): 3.99e-50: 167: 31.32
+	Hs
		896567 UBE2N_HUMAN (4-147): 3.74e-68: 204: 47.22		CHIP_HUMAN (3-275): 6.02e-59: 191: 31.47
+	Zm
		31012 B4FC97_MAIZE (1-148): 1.21e-83: 243: 93.24		A0A1D6KE36_MAIZE (41-271): 5.17e-40: 148: 21.01
+	Zm
		14055 A0A1D6G0U5_MAIZE (1-113): 1.4e-73: 218: 93.81		A0A1D6LII0_MAIZE (8-276): 9.76e-51: 170: 51.58
+	Ce
		105590 UBC13_CAEEL (4-146): 5.24e-42: 138: 48.25		G5ECY6_CAEEL (10-274): 3.99e-50: 167: 31.32
+	Hs
		684581 UBE2N_HUMAN (4-147): 3.74e-68: 204: 47.22		STIP1_HUMAN (9-132): 2.76e-16: 80.5: 23.66