HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.710

The method score is based on:

Property Details
Experiments 21411634, 28581508, 11532964, 37840274, 16716190
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0031623 - receptor internalization
GO:0070062 - extracellular exosome
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 777
Hs

1 1675
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs
+ Zm
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025