HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: UBP2L (Q14157)
Ubiquitin-associated protein 2-like (Protein NICE-4) (RNA polymerase II degradation factor UBAP2L)
Gene: UBAP2L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	24457600, 27647897, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031519 - PcG protein complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 1087
+	Hs
		554277 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MUC1_HUMAN (398-1087): 1.12e-39: 162: 13.41
+	Hs
		718128 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MINT_HUMAN (101-1064): 1.9e-36: 152: 12.71
+	Hs
		183149 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		KDM6A_HUMAN (312-801): 9.06e-90: 317: 17.64
+	Mm
		251040 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		KDM6A_MOUSE (362-801): 4.97e-81: 292: 17.75
+	Hs
		1056961 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		MDC1_HUMAN (146-1087): 1.69e-21: 103: 9.23
+	Hs
		1244297 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		ARI1B_HUMAN (278-1077): 7.19e-14: 78.6: 13.35
+	Hs
		1316711 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		RERE_HUMAN (539-1062): 5.65e-10: 65.8: 11.20
+	Hs
		282505 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		TPR_HUMAN (8-958): 1.6e-35: 149: 11.80
+	Hs
		1223393 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		RERE_HUMAN (539-1062): 5.65e-10: 65.8: 11.20
+	Hs
		282654 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		MDC1_HUMAN (146-1087): 1.69e-21: 103: 9.23
+	Hs
		987995 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		KMT2C_HUMAN (236-1079): 9.68e-11: 68.8: 10.84