HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: DIC (Q9UBX3)
Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10)
Gene: SLC25A10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27025967
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 287
+	Mm
		1265153 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		DIC_MOUSE (3-287): 7.72e-92: 275: 90.18
+	Hs
		397287 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		ADT2_HUMAN (94-281): 1.4e-35: 131: 19.00
+	Hs
		518263 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		ADT3_HUMAN (94-281): 1.12e-35: 131: 18.50
+	Hs
		718773 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		M2OM_HUMAN (91-281): 3.11e-34: 128: 21.11
+	Hs
		719218 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		274497 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		S2512_HUMAN (10-102): 2.53e-19: 89.4: 20.62
+	Hs
		1305308 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		S2513_HUMAN (10-102): 8.09e-20: 91: 21.65
+	Hs
		274609 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		S2512_HUMAN (10-102): 2.53e-19: 89.4: 20.62
+	Mm
		823136 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		ADT1_MOUSE (93-281): 9.1e-37: 134: 18.41
+	Mm
		851105 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		ADT2_MOUSE (94-281): 7.92e-36: 131: 19.00
+	Mm
		1265151 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		S2513_MOUSE (10-102): 8.72e-20: 91: 22.68
+	Mm
		1206505 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		S2512_MOUSE (10-102): 2.13e-19: 89.8: 21.65
+	Mm
		1206892 PODO_MOUSE (1-271): 4.92e-65: 209: 16.42		SCMC1_MOUSE (189-281): 4.79e-17: 82.5: 21.28