HitPredict

Interactor 1: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Interactor 2: PSF3 (Q12146)
DNA replication complex GINS protein PSF3 (Partner of Sld five 3)
Gene: PSF3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 24805245, 26255844, 27397685, 19661920, 19913425, 37968396, 38776358, 21362622, 21868389, 23499531
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0031261 - DNA replication preinitiation complex
GO:0043596 - nuclear replication fork
GO:0071162 - CMG complex
and 1 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 933
Sc

1 194
+ Dm
+ Sc
+ Sc
+ Sc
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025