Protein: PSF3
DNA replication complex GINS protein PSF3 (GINS complex subunit 3)

Gene: PSF3, GINS3
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q9BRX5

Gene Ontology (top 5):
GO:0000811 - GINS complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035264 - multicellular organism growth
GO:0071162 - CMG complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1130908

PSF1
DNA replication complex GINS protein PSF1

8

3

Small-scale

0.964

High

1411865

SLD5
DNA replication complex GINS protein SLD5

6

4

Small-scale

0.946

High

1411976

PSF2
DNA replication complex GINS protein PSF2

4

3

Small-scale

0.899

High

756325

MCM7
DNA replication licensing factor MCM7

3

10

High-throughput

0.861

High

888290

MCM2
DNA replication licensing factor MCM2

3

9

Small-scale

0.853

High

281244

CDC45
Cell division control protein 45 homolog

2

2

Small-scale

0.789

High

1128269

MCM6
DNA replication licensing factor MCM6

1

10

Small-scale

0.647

High

1065397

SSRP1
FACT complex subunit SSRP1

3

0

High-throughput

0.646

High

1411968

TIPIN
TIMELESS-interacting protein

3

0

High-throughput

0.638

High

1411969

CLSPN
Claspin

3

0

High-throughput

0.638

High

1411975

TIM
Protein timeless homolog

3

0

High-throughput

0.638

High

591819

H2AX
Histone H2AX

2

1

High-throughput

0.628

High

1006944

KC1G2
Casein kinase I isoform gamma-2

2

0

High-throughput

0.602

High

1392043

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.580

High

315953

RECQ4
ATP-dependent DNA helicase Q4

2

0

Small-scale

0.559

High

254418

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.536

High

1017169

H33
Histone H3.3

1

1

High-throughput

0.536

High

1372467

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.536

High

1381853

H2B1A
Histone H2B type 1-A

1

1

High-throughput

0.536

High

564295

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

274727

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.515

High

709005

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.513

High

1052907

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.513

High

160010

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

167381

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

856891

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

1359388

DNJB3
DnaJ homolog subfamily B member 3

1

1

High-throughput

0.489

High

894126

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

419176

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

981054

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

998747

H31
Histone H3.1

1

1

High-throughput

0.479

High

242746

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

260380

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

373002

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

1411970

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.458

High

1411971

DONS
Protein downstream neighbor of Son

1

0

Small-scale

0.458

High

1411972

RTEL1
Regulator of telomere elongation helicase 1

1

0

Small-scale

0.458

High

1411978

MAFB
Transcription factor MafB

1

0

High-throughput

0.458

High

1232547

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.457

High

1066009

VAC14
Protein VAC14 homolog

3

0

High-throughput

0.348

High

295999

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.316

High

1235622

K2C80
Keratin, type II cytoskeletal 80

2

0

High-throughput

0.316

High

1411973

CTNA3
Catenin alpha-3

2

0

High-throughput

0.316

High

1208235

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

578004

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.268

Low

1395453

MY15B
Unconventional myosin-XVB

1

0

High-throughput

0.268

Low

1411967

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1411974

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.268

Low

675130

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.249

Low

914333

EFNA4
Ephrin-A4

1

0

High-throughput

0.249

Low

1255287

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1331427

MB213
Protein mab-21-like 3

1

0

High-throughput

0.232

Low

1411977

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025