HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	9368759
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006409 - tRNA export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 1317
+	Hs
		172308 XPO1_HUMAN (3-1084): 0: 853: 46.77		GANP_HUMAN (5-391): 1.16e-17: 91.6: 13.36
+	Hs
		172603 XPO1_HUMAN (3-1084): 0: 853: 46.77		NUP98_HUMAN (54-517): 2.93e-13: 77: 9.02
+	Hs
		172585 XPO1_HUMAN (3-1084): 0: 853: 46.77		NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97
+	Hs
		172516 XPO1_HUMAN (3-1084): 0: 853: 46.77		NU214_HUMAN (4-435): 7.79e-11: 69.3: 12.18
+	Hs
		172610 XPO1_HUMAN (3-1084): 0: 853: 46.77		SC24C_HUMAN (2-199): 8.72e-11: 68.9: 11.82
+	Hs
		172347 XPO1_HUMAN (3-1084): 0: 853: 46.77		SC24D_HUMAN (244-551): 1.01e-10: 68.5: 8.78
+	Sc
		722003 XPO1_YEAST (1-1084): 0: 832: 100.00		NU159_YEAST (2-476): 5.67e-17: 89.3: 13.99
+	Xl
		1225351 Q6NS03_XENLA (3-1084): 0: 851: 47.14		Q641I5_XENLA (2-152): 4.37e-09: 63.2: 9.09
+	Sc
		722081 XPO1_YEAST (1-1084): 0: 832: 100.00		NUP57_YEAST (73-482): 1.45e-13: 77: 17.65
+	Sc
		577273 XPO1_YEAST (1-1084): 0: 832: 100.00		NSP1_YEAST (1-448): 5.02e-13: 75.8: 15.01
+	Sc
		722188 XPO1_YEAST (1-1084): 0: 832: 100.00		NU116_YEAST (2-495): 2.23e-10: 67.4: 14.34
+	Sc
		722187 XPO1_YEAST (1-1084): 0: 832: 100.00		NU100_YEAST (2-480): 2.86e-10: 67: 13.04
+	Sc
		722181 XPO1_YEAST (1-1084): 0: 832: 100.00		NUP49_YEAST (3-140): 3.58e-10: 66.1: 29.68
+	Sc
		722083 XPO1_YEAST (1-1084): 0: 832: 100.00		NUP42_YEAST (2-285): 1.66e-09: 63.8: 17.86
+	Dm
		1457450 XPO1_DROME (3-1084): 0: 788: 42.48		Q9VLS7_DROME (4-460): 3.43e-09: 63.9: 11.57
+	Tt
		107489 G0RZB7_CHATD (10-1084): 0: 778: 50.19		NU145_CHATD (4-479): 5.88e-10: 66.2: 12.16
+	Hs
		1047136 XPO7_HUMAN (11-1030): 3.3e-146: 467: 13.77		IF4G1_HUMAN (52-738): 1.44e-52: 205: 10.11
+	Hs
		890412 XPO7_HUMAN (11-1030): 3.3e-146: 467: 13.77		NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97
+	Hs
		1368514 XPO7_HUMAN (11-1030): 3.3e-146: 467: 13.77		CBP_HUMAN (13-485): 2.05e-10: 67.7: 8.61
+	Mm
		1240001 XPO7_MOUSE (11-1030): 7.53e-146: 466: 13.68		IF4G1_MOUSE (213-740): 6.31e-10: 66.2: 7.84