HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NUP49 (Q02199)
Nucleoporin NUP49/NSP49 (Nuclear pore protein NUP49/NSP49)
Gene: NUP49

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	11387327, 9368759, 18573877
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000055 - ribosomal large subunit export from nucleus GO:0006409 - tRNA export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 472
+	Hs
		172308 XPO1_HUMAN (3-1084): 0: 853: 46.77		GANP_HUMAN (3-461): 1.32e-46: 175: 14.31
+	Hs
		173300 XPO1_HUMAN (3-1084): 0: 853: 46.77		NUP58_HUMAN (22-450): 7.31e-33: 133: 15.44
+	Hs
		172610 XPO1_HUMAN (3-1084): 0: 853: 46.77		SC24C_HUMAN (4-278): 4.24e-31: 129: 14.75
+	Hs
		172603 XPO1_HUMAN (3-1084): 0: 853: 46.77		NUP98_HUMAN (124-327): 9.62e-18: 88.7: 14.67
+	Hs
		172585 XPO1_HUMAN (3-1084): 0: 853: 46.77		NU153_HUMAN (1-243): 4.42e-17: 86.7: 18.00
+	Hs
		172516 XPO1_HUMAN (3-1084): 0: 853: 46.77		NU214_HUMAN (9-247): 6.32e-16: 82.9: 22.39
+	Sc
		722084 XPO1_YEAST (1-1084): 0: 832: 100.00		NU145_YEAST (1-351): 5.21e-20: 95.7: 16.76
+	Sc
		722187 XPO1_YEAST (1-1084): 0: 832: 100.00		NU100_YEAST (1-363): 1.46e-17: 87.9: 20.00
+	Sc
		722081 XPO1_YEAST (1-1084): 0: 832: 100.00		NUP57_YEAST (17-256): 3.3e-17: 85.9: 32.67
+	Sc
		722003 XPO1_YEAST (1-1084): 0: 832: 100.00		NU159_YEAST (2-419): 1.69e-10: 65.6: 12.88
+	Sc
		722188 XPO1_YEAST (1-1084): 0: 832: 100.00		NU116_YEAST (1-276): 9.64e-09: 59.8: 20.85
+	Tt
		107489 G0RZB7_CHATD (10-1084): 0: 778: 50.19		NU145_CHATD (18-328): 2.37e-10: 65.2: 20.67
+	Hs
		1415480 XPO7_HUMAN (11-1030): 3.3e-146: 467: 13.77		NUP58_HUMAN (22-450): 7.31e-33: 133: 15.44
+	Hs
		890412 XPO7_HUMAN (11-1030): 3.3e-146: 467: 13.77		NU153_HUMAN (1-243): 4.42e-17: 86.7: 18.00
+	Hs
		916012 TNPO1_HUMAN (21-967): 3.83e-125: 406: 12.09		NUP98_HUMAN (124-327): 9.62e-18: 88.7: 14.67
+	Hs
		775626 TNPO3_HUMAN (8-1040): 2.32e-126: 410: 13.22		NU214_HUMAN (9-247): 6.32e-16: 82.9: 22.39
+	Hs
		890382 TNPO1_HUMAN (21-967): 3.83e-125: 406: 12.09		NU153_HUMAN (1-243): 4.42e-17: 86.7: 18.00
+	Hs
		775585 TNPO1_HUMAN (21-967): 3.83e-125: 406: 12.09		NU214_HUMAN (9-247): 6.32e-16: 82.9: 22.39
+	Hs
		164551 TNPO2_HUMAN (21-956): 1.54e-115: 380: 11.98		NUP98_HUMAN (124-327): 9.62e-18: 88.7: 14.67
+	Hs
		164548 TNPO2_HUMAN (21-956): 1.54e-115: 380: 11.98		NU153_HUMAN (1-243): 4.42e-17: 86.7: 18.00